1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyrazine - Names and Identifiers
Name | 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
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Synonyms | 5H,6H,7H,8H-imidazo[1,5-a]pyrazine 4H,5H,6H,7H-iMidazo[1,5-a]pyrazine 5,6,7,8-tetrahydroimidazo[1,5-A]pyrazin 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine imidazo[1,5-a]pyrazine, 5,6,7,8-tetrahydro- IMidazo[1,5-a]pyrazine, 5,6,7,8-tetrahydro- 5,6,7,8-Tetrahydroimidazolo[1,5-a]piperazine 1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyrazine Imidazo[1,5-a]pyrazine, 5,6,7,8-tetrahydro- (9CI)
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CAS | 297172-19-1
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InChI | InChI=1/C6H9N3/c1-2-9-5-8-4-6(9)3-7-1/h4-5,7H,1-3H2
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1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyrazine - Physico-chemical Properties
Molecular Formula | C6H9N3
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Molar Mass | 123.16 |
Density | 1.33±0.1 g/cm3(Predicted) |
Boling Point | 340.0±30.0 °C(Predicted) |
Flash Point | 159.4°C |
Vapor Presure | 8.84E-05mmHg at 25°C |
pKa | 8.26±0.20(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.689 |
1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyrazine - Introduction
5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine is an organic compound with the chemical formula C6H8N2. The following is a description of the properties, uses, preparation and safety information of the compound:
1. Nature:
-Appearance: 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine is a colorless crystalline solid.
-Solubility: It has high solubility in regular organic solvents.
-Melting point: The melting point range of this compound is about 60-65°C.
-Stability: It is more stable to oxygen and light.
2. Use:
-Drug research: 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine is an important intermediate that can be used to synthesize anti-cancer drugs and other drugs.
-Pesticide: It can also be used to synthesize certain pesticides.
3. Preparation method:
-A common preparation method is to react imidazole with 1,2-dibromoethane to generate 5,6, 7,8-tetrabromoimidazole [1,5-a] pyrazine, subsequent reduction or ammonolysis reactions give the target product.
-There are other synthetic routes and methods, but the commonly used preparation method is through the above route.
4. Safety Information:
- 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine is generally relatively safe under correct operation.
-Comply with relevant laboratory safety practices when using and handling compounds.
-It is recommended that appropriate personal protective equipment, such as gloves, glasses and laboratory coats, be worn at the time of use.
-Avoid contact with skin and eyes, and prevent inhalation or ingestion of the compound.
-In use, storage and handling to maintain a well-ventilated environment, avoid contact with oxygen or fire.
This information provides an introduction to the basic properties, uses, preparation and safety information of 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine. However, in the specific application, the specific conditions of the compound and the recommend laboratory procedures need to be further considered.
Last Update:2024-04-09 20:13:35